https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Impact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetuses https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24304 485) (P < 0.01), p-PDPK-1 (Ser⁴¹) (P < 0.05), and PKCζ (P < 0.05) was higher in the PCUN and PIUN groups, and hepatic PDK4 (P < 0.001) and CPT-1 (P < 0.05) protein abundance was also higher in the PIUN twin fetus. We also found that the expression of a number of microRNAs was altered in response to PCUN or PIUN and that there is evidence that these changes may underlie the changes in the protein abundance of key regulators of hepatic fatty acid β-oxidation in the PCUN and PIUN groups. Therefore, embryo number and the timing of maternal undernutrition in early pregnancy have a differential impact on hepatic microRNA expression and on the factors that regulate hepatic fatty acid oxidation and lipid synthesis.]]> Wed 28 Feb 2024 15:22:08 AEDT ]]> Impact of periconceptional and preimplantation undernutrition on factors regulating myogenesis and protein synthesis in muscle of singleton and twin fetal sheep https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27351 Wed 11 Apr 2018 13:32:44 AEST ]]> Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20824 Sat 24 Mar 2018 08:05:56 AEDT ]]> The Australian early origins of hypertension workshop: a celebration of the scientific contributions made by Emeritus Scientia Professor Eugenie R Lumbers AM and Professor Caroline McMillen https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17403 Sat 24 Mar 2018 08:01:28 AEDT ]]> Embryo number and periconceptional undernutrition in the sheep have differential effects on adrenal epigenotype, growth, and development https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20508 Sat 24 Mar 2018 07:59:05 AEDT ]]> Periconceptional undernutrition programs changes in insulin-signaling molecules and microRNAs in skeletal muscle in singleton and twin fetal sheep https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20984 Sat 24 Mar 2018 07:50:31 AEDT ]]>